NCLEX_CRUSADE_ACADEMY TEST - 15 PEAK_AND_TROUGH_VALUES_OF_ANTIBIOTICS_+

1. The primary purpose of therapeutic drug monitoring is to: Reduce hospital stay. Individualize dosing and prevent toxicity. Increase drug cost. Replace physician judgment.

2. Which antibiotic families most commonly require peak and trough monitoring?. Macrolides. Aminoglycosides and Vancomycin. Penicillins. Sulfonamides.

3. A peak drug level represents: Minimum concentration before the next dose. Maximum drug concentration after infusion. Drug elimination rate. Drug half-life.

4. A trough drug level represents: Maximum drug concentration. Minimum concentration before next dose. Average drug concentration. Drug metabolism rate.

5. When should the nurse draw a peak level for IV antibiotics?. Immediately before infusion. 30 minutes after infusion finishes. 2 hours after dose. Immediately after administration.

6. When should a trough level be drawn?. Immediately after infusion. 1 hour after infusion. 30 minutes before the next dose. 4 hours after dose.

7. Accurate timing of peak and trough draws is important because: It determines drug color. It affects the validity of the results. It reduces drug cost. It eliminates side effects.

8. If a trough level is reported as critically high, the nurse should: Administer the next dose immediately. Hold the medication and notify the provider. Ignore the result. Increase the dose.

9. High trough levels indicate: Subtherapeutic dosing. Drug toxicity risk. Rapid drug metabolism. Drug ineffectiveness.

10. Low peak levels generally indicate: Toxicity. Ineffective therapy. Kidney failure. Drug overdose.

11. Vancomycin therapeutic trough range is approximately: 15 mcg/mL. 510 mcg/mL. 1520 mcg/mL. 3040 mcg/mL.

12. The major toxicity risks associated with vancomycin include: Hepatotoxicity. Nephrotoxicity and ototoxicity. Cardiotoxicity. Pulmonary toxicity.

13. Which symptom may indicate ototoxicity?. Headache. Tinnitus. Constipation. Fever.

14. Which lab values should be monitored to detect nephrotoxicity?. AST and ALT. BUN and creatinine. Hemoglobin. Sodium.

15. The purpose of therapeutic drug monitoring is NOT to: Prevent toxicity. Ensure therapeutic range. Replace clinical judgment. Individualize dosing.

16. In isolation prioritization, which transmission type requires the highest priority?. Contact. Droplet. Airborne. Standard.

17. A patient with symptomatic varicella should be placed in: Standard precautions. Droplet precautions. Airborne isolation. Contact precautions.

18. Negative pressure rooms are required for: Droplet infections. Contact infections. Airborne infections. Bloodborne infections.

19. Which infection requires airborne precautions?. MRSA. Tuberculosis. Influenza. C. difficile.

20. According to isolation prioritization logic, symptomatic patients should: Wait for diagnosis. Be isolated first. Share rooms. Remain untreated.

21. Arboviral encephalitis is transmitted by: Respiratory droplets. Mosquito vectors. Direct contact. Food contamination.

22. Antibiotics are ineffective against arboviral encephalitis because: The disease is fungal. It is viral. It is bacterial. It is parasitic.

23. The priority intervention for arboviral encephalitis is: Antibiotics. Seizure precautions. Isolation. Oxygen therapy.

24. In SARS infection control, the highest priority is: Patient comfort. Public safety. Nurse safety. Visitor access.

25. SARS requires which type of precautions?. Contact only. Droplet only. Airborne and contact. Standard precautions.

26. Required PPE for SARS includes: Gloves only. N95 mask, gown, gloves, eye protection. Mask only. Apron only.

27. If a physician leaves a patient room without performing hand hygiene, the nurse should: Report immediately to management. Ignore it. Offer alcohol gel immediately. Document later.

28. The goal of addressing infection control breaches immediately is to: Prevent confrontation. Prevent transmission. Reduce documentation. Save time.

29. In therapeutic drug monitoring, incorrect timing of blood draws may lead to: Increased drug effectiveness. Invalid lab results. Faster drug elimination. Reduced toxicity.

30. A nurse reviewing antibiotic therapy should prioritize: Drug color. Drug smell. Safety and toxicity monitoring. Medication packaging.